Affimed (AFMD)

Affimed N.V., a clinical-stage biopharmaceutical company, focuses on discovering and developing cancer immunotherapies in the United States and Germany. The company's lead product candidates include AFM13, which has completed a Phase 2 clinical trial for CD30-positive lymphoma, a Phase Ib clinical trial for Hodgkin lymphoma, and a completed Phase IIb clinical study for peripheral T-cell lymphoma. Another candidate, AFM24, is a tetravalent, bispecific epidermal growth factor receptor and CD16A-binding innate cell engager, which is currently in a Phase IIa clinical trial for the treatment of advanced cancers. Additionally, AFM28, an innate cell engager (ICE), is in preclinical development for the treatment of acute myeloid leukemia. The company is also developing AFM32, an ICE candidate that is in preclinical development for the treatment of solid tumors. Affimed N.V. has collaborations with Artiva Biotherapeutics to develop the combination of acimtamig and AlloNK. It has a license and strategic collaboration agreement with Roivant Sciences Ltd. to develop and commercialize novel ICE molecules, including AFM32, in oncology. Furthermore, there is a strategic collaboration agreement with Genentech for the development of certain product candidates, which includes novel NK cell engager-based immunotherapeutics to treat multiple cancers. The company was formerly known as Affimed Therapeutics B.V. and changed its name to Affimed N.V. in October 2014. Affimed N.V. was founded in 2000 and is headquartered in Mannheim, Germany.