PepGen (PEPG)

Take Impact Assessment
Overall impact
C (53)

Commentary

PepGen is an average overall performer. With a 'C' rating of 53.2 for overall impact (48th percentile compared to all companies), PepGen ranks 596th out of 669 industry peers, behind Curium Pharma, Allena Pharmaceuticals, Pluristem Therapeutics and 592 others, and ahead of Aldeyra Therapeutics, Aptose Biosciences, Apellis Pharmaceuticals and 70 others. On top material causes for PepGen's industry (Biotechnology), PepGen performs well in Disease Eradication (96.2 score), Access to Affordable Healthcare (89.6), Child and Maternal Health (95.3) and 7 other causes where it received an 'A' score and performs poorly in Accountable Institutions (30.5 score), Accountable Institutions (30.5), Accountable Institutions (30.5) and 16 other causes where it received a 'D' or 'F' score.
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Screens
Advertising
Alcohol
Alcohol - responsible marketing
Animal treatment
Anti-abortion support
Anti-Israel
Anti-personnel mines
Anti-social publishing
Arctic drilling
Banned pesticides and chemicals
Banned pharmaceuticals
Biological and chemical weapons
Cannabis
Carbon emissions intensity
Child safety
Cluster munitions
Coal
Conflict minerals
Contraceptives
Controversial weapons
Deforestation - financing
Deforestation - supply chain
Depleted uranium
Discrimination controversies
Electrical utility
Endangered wildlife
Environmental controversies
EU sanctions list
Factory farming
Fast food
Firearms
Food commodity derivatives
For-profit health care
Fossil fuel
Fur
Gambling
Genetic engineering
Health-related controversies
Human rights controversies
Human trafficking
Illegal activities
ILO Conventions
Interest-based products
Iran
Land use and biodiversity
Military contracting
Misleading communication
Music
Myanmar
Non-sustainable palm oil
Northern Ireland (Macbride)
North Korea
No SBTI commitment
Nuclear
OECD Guidelines
Oil and gas
Opioid controversies
Oppressive governments
Palestinian human rights
Pharma controversies
Pork
Pornography
Predatory lending
Prison involvement
Privacy breaches
Pro-life
Russia
Single-use plastic
Stem cell research
Sudan
Sugar
Syria
Tar sands
Thermal coal
Tobacco
Tobacco - GICS
UK sanctions list
Undermining US elections
UN Global Compact
UN Guiding Principles
US OFAC sanctions list
Weapons
Impact
Cause PEPG
Peer rank
Overall impact

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Screens
Advertising
Alcohol
Alcohol - responsible marketing
Animal treatment
Anti-abortion support
Anti-Israel
Anti-personnel mines
Anti-social publishing
Arctic drilling
Banned pesticides and chemicals
Banned pharmaceuticals
Biological and chemical weapons
Cannabis
Carbon emissions intensity
Child safety
Cluster munitions
Coal
Conflict minerals
Contraceptives
Controversial weapons
Deforestation - financing
Deforestation - supply chain
Depleted uranium
Discrimination controversies
Electrical utility
Endangered wildlife
Environmental controversies
EU sanctions list
Factory farming
Fast food
Firearms
Food commodity derivatives
For-profit health care
Fossil fuel
Fur
Gambling
Genetic engineering
Health-related controversies
Human rights controversies
Human trafficking
Illegal activities
ILO Conventions
Interest-based products
Iran
Land use and biodiversity
Military contracting
Misleading communication
Music
Myanmar
Non-sustainable palm oil
Northern Ireland (Macbride)
North Korea
No SBTI commitment
Nuclear
OECD Guidelines
Oil and gas
Opioid controversies
Oppressive governments
Palestinian human rights
Pharma controversies
Pork
Pornography
Predatory lending
Prison involvement
Privacy breaches
Pro-life
Russia
Single-use plastic
Stem cell research
Sudan
Sugar
Syria
Tar sands
Thermal coal
Tobacco
Tobacco - GICS
UK sanctions list
Undermining US elections
UN Global Compact
UN Guiding Principles
US OFAC sanctions list
Weapons
Impact trend

Change in rating for overall impact

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Company
Employees
57
Sector
Health Care
Industry
Biotechnology
Sub-industry
Biotechnology
SASB industry
Biotechnology & Pharmaceuticals
Headquarters
Ma, United States
Share classes
PEPG
More info
https://www.pepgen.com
Description
PepGen Inc., a clinical-stage biotechnology company, develops oligonucleotide therapeutics for the treatment of severe neuromuscular and neurologic diseases in the United States. Its lead product candidates comprise PGN-EDO51, an EDO peptide which is Phase 2 clinical trial to treat duchenne muscular dystrophy (DMD) patients that are amenable to an exon 51-skipping approach; PGN-EDODM1, an EDO peptide-conjugated PMO, which is in Phase 2 clinical trial for the treatment of myotonic dystrophy type 1; and PGN-EDO53, which is in preclinical trial to treat duchenne muscular dystrophy. The company was founded in 2018 and is based in Boston, Massachusetts.
Material causes
Ethos considers the following causes material for PepGen, based on its industry sub-industry Biotechnology. Learn more about material causes in our methodology overview.
Access to affordable healthcare
Ensure universal access to affordable, quality healthcare
Accountable institutions
Build accountable and inclusive institutions at all levels
Child and maternal health
End preventable deaths of mothers and children, support reproductive health everywhere
Decent, safe work opportunities
Promote full and productive employment for all, in safe work environments
Disaster readiness and effective aid
Be prepared for natural disasters and provide effective aid when disasters happen
Disease eradication
Eradicate infectious and non-communicable diseases
Equal pay and opportunity
Achieve equal pay and opportunity for women everywhere
Free, secure flow of information
Ensure a free and open flow of information, with secure personal data and privacy
Humane treatment of animals
Ensure humane treatment of animals everywhere
Improved mental health
Support awareness and access to mental health support for all
Quality lifelong education
Ensure access to quality secondary education and lifelong learning opportunities for all
Racial justice and civil rights
Eliminate racism and ensure justice for all
Reduced green house gas emissions
Continually reduce green house gas emissions and other pollutants
Reduced use of tobacco
Continually reduce the use of tobacco
Reduced waste
Reduce waste and support re-usable materials
Sustainable use of natural resources
Ensure sustainable use of natural resources
Sustainable use of water
Promote sustainable management of water everywhere
Technology innovation
Foster technology innovation that supports sustainable economic development
Health and well-being
Ensure healthy lives and promote well-being for all at all ages
Peace and justice
Promote peaceful and inclusive societies, provide access to justice for all
Inclusive economies
Create inclusive economies with no poverty, decent work for all, and affordable living conditions
Climate action
Take urgent action to combat climate change and its impacts
Gender equality
Achieve gender equality and empower all women and girls
Innovation
Innovate to foster economic growth and human development
Life on earth
Protect biodiversity and ensure sustainable use of ecosystems
Quality education
Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all
Sustainable resource use
Ensure sustainable consumption and production patterns
Water and sanitation
Ensure availability and sustainable management of water and sanitation for all

This information is subject to Ethos' Terms and Conditions, which you can find here.

This information may not be used for corporate financing purposes (including, without limitation, ESG-linked loans, credit facilities, securities or structured products), as a basis for any financial instruments or products (including, without limitation, passively managed funds and index-linked derivative securities) or other products or services, to verify or correct data in any other compilation of data or index, to create any derivative works, nor to create any other data or index (custom or otherwise), without Ethos' prior written permission.

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