Aprea Therapeutics (APRE)

Take Impact Assessment
Overall impact
B (61)

Commentary

Aprea Therapeutics is a strong overall performer. With a 'B' rating of 61.0 for overall impact (65th percentile compared to all companies), Aprea Therapeutics ranks 22nd out of 33 industry peers, behind Zoetis, Adamas Pharmaceuticals, Ironwood Pharmaceuticals and 18 others, and ahead of Horizon Pharma, Agile Therapeutics, Karyopharm Therapeutics and 8 others. On top material causes for Aprea Therapeutics's industry (Pharmaceuticals & Biotech), Aprea Therapeutics performs well in Improved Mental Health (84.2 score), Disease Eradication (96.4), Child and Maternal Health (84.2) and 2 other causes where it received an 'A' score and performs poorly in Accountable Institutions (26.0 score), Reduced Green House Gas Emissions (20.7), Humane Treatment of Animals (0.0) and 1 other cause where it received a 'D' or 'F' score.
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Alcohol
Alcohol - responsible marketing
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Anti-Israel
Anti-personnel mines
Arctic drilling
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Biological and chemical weapons
Cannabis
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Child safety
Cluster munitions
Coal
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Deforestation - financing
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Depleted uranium
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Endangered wildlife
Environmental controversies
EU sanctions list
Factory farming
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Human trafficking
ILO Conventions
Interest-based products
Interest-bearing debt
Interest-bearing securities
Iran
Land use and biodiversity
Military contracting
Misleading communication
Modern slavery
Music
Myanmar
Non-sustainable palm oil
Norges Bank exclusion list
Northern Ireland (Macbride)
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No SBTI commitment
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OECD Guidelines
Oil and gas
Opioid controversies
Oppressive governments
Palestinian human rights
Pharma controversies
Pork
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Pro-life
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Single-use plastic
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Tar sands
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Undermining US elections
UN Global Compact
UN Guiding Principles
US OFAC sanctions list
Weapons
Impact
Cause APRE
Peer rank
Overall impact

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Screens
Advertising
Alcohol
Alcohol - responsible marketing
Animal treatment
Anti-abortion support
Anti-Israel
Anti-personnel mines
Arctic drilling
Banned pesticides and chemicals
Biological and chemical weapons
Cannabis
Carbon emissions intensity
Child safety
Cluster munitions
Coal
Contraceptives
Controversial weapons
Deforestation - financing
Deforestation - supply chain
Depleted uranium
Discrimination controversies
Electrical utility
Endangered wildlife
Environmental controversies
EU sanctions list
Factory farming
Fast food
Firearms
Food commodity derivatives
For-profit health care
Fossil fuel
Fur
Gambling
Genetic engineering
Health-related controversies
Human rights controversies
Human trafficking
ILO Conventions
Interest-based products
Interest-bearing debt
Interest-bearing securities
Iran
Land use and biodiversity
Military contracting
Misleading communication
Modern slavery
Music
Myanmar
Non-sustainable palm oil
Norges Bank exclusion list
Northern Ireland (Macbride)
North Korea
No SBTI commitment
Nuclear
OECD Guidelines
Oil and gas
Opioid controversies
Oppressive governments
Palestinian human rights
Pharma controversies
Pork
Pornography
Predatory lending
Prison involvement
Privacy breaches
Pro-life
Russia
Single-use plastic
Stem cell research
Sudan
Sugar
Syria
Tar sands
Thermal coal
Tobacco
Tobacco - GICS
UK sanctions list
Undermining US elections
UN Global Compact
UN Guiding Principles
US OFAC sanctions list
Weapons
Impact trend

Change in rating for overall impact

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Company
Employees
8
Sector
Health Care
Industry
Pharmaceuticals
Sub-industry
Pharmaceuticals
SASB industry
Biotechnology & Pharmaceuticals
Headquarters
Pa, United States
Share classes
APRE
More info
https://aprea.com
Description
Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers; and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in Doylestown, Pennsylvania.
Material causes
Ethos considers the following causes material for Aprea Therapeutics, based on its industry sub-industry Pharmaceuticals. Learn more about material causes in our methodology overview.
Access to affordable healthcare
Ensure universal access to affordable, quality healthcare
Accountable institutions
Build accountable and inclusive institutions at all levels
Child and maternal health
End preventable deaths of mothers and children, support reproductive health everywhere
Decent, safe work opportunities
Promote full and productive employment for all, in safe work environments
Disaster readiness and effective aid
Be prepared for natural disasters and provide effective aid when disasters happen
Disease eradication
Eradicate infectious and non-communicable diseases
Equal pay and opportunity
Achieve equal pay and opportunity for women everywhere
Fair labor practices
Ensure fair and humane labor practices everywhere
Humane treatment of animals
Ensure humane treatment of animals everywhere
Improved mental health
Support awareness and access to mental health support for all
Racial justice and civil rights
Eliminate racism and ensure justice for all
Reduced green house gas emissions
Continually reduce green house gas emissions and other pollutants
Reduced inequality
Reduce inequality within and among countries
Reduced use of tobacco
Continually reduce the use of tobacco
Reduced waste
Reduce waste and support re-usable materials
Sustainable use of natural resources
Ensure sustainable use of natural resources
Sustainable use of water
Promote sustainable management of water everywhere
Technology innovation
Foster technology innovation that supports sustainable economic development
Health and well-being
Ensure healthy lives and promote well-being for all at all ages
Peace and justice
Promote peaceful and inclusive societies, provide access to justice for all
Inclusive economies
Create inclusive economies with no poverty, decent work for all, and affordable living conditions
Climate action
Take urgent action to combat climate change and its impacts
Gender equality
Achieve gender equality and empower all women and girls
Life on earth
Protect biodiversity and ensure sustainable use of ecosystems
Sustainable resource use
Ensure sustainable consumption and production patterns
Water and sanitation
Ensure availability and sustainable management of water and sanitation for all
Innovation
Innovate to foster economic growth and human development

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